Crescono i sospetti che le nanoparticelle nel vaccino COVID-19 di Pfizer inneschino rare reazioni allergiche
Some people suspect polyethylene glycol may have triggered severe reactions in at least eight people who received the Pfizer-BioNTech vaccine in the past 2 weeks.
Suspicions grow that nanoparticles in Pfizer’s COVID-19 vaccine trigger rare allergic reactions
Science’s COVID-19 reporting is supported by the Pulitzer Center and the Heising-Simons Foundation.
Severe allergy-like reactions in at least eight people who received the COVID-19 vaccine produced by Pfizer and BioNTech over the past 2 weeks may be due to a compound in the packaging of the messenger RNA (mRNA) that forms the vaccine’s main ingredient, scientists say. A similar mRNA vaccine developed by Moderna, which was authorized for emergency use in the United States on Friday, also contains the compound, polyethylene glycol (PEG).
PEG has never been used before in an approved vaccine, but it is
found in many drugs that have occasionally triggered anaphylaxis—a
potentially life-threatening reaction that can cause rashes, a
plummeting blood pressure, shortness of breath, and a fast heartbeat.
Some allergists and immunologists believe a small number of people
previously exposed to PEG may have high levels of antibodies against
PEG, putting them at risk of an anaphylactic reaction to the vaccine.
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